God speaks to a young virgin girl, Mary, through the angel Gabriel. This important message relayed God's favor for Mary. As Mary did not desire this calling of bearing the Son of God, the Messiah, we can glean the significance of God's sovereign calling and Mary's faithful submission to God's will. God wanted Mary to be the Theotokos, the "mother of God". Gabriel's final words of comfort for Mary are in Luke 1:37, "For nothing will be impossible with God."