Episode description

The cardiovascular system is the first to function, and its development sets the tempo for everything that follows. In this episode, we explore how a simple linear tube becomes a four-chambered heart, capable of supporting the growing embryo long before birth.

Langman clarifies looping, septation, and signalling pathways; IB Singh provides the essential structural sequencing; and Moore grounds the discussion in congenital heart disease, arch derivatives, and foetal circulation. Rather than listing defects, we focus on how small deviations in timing or alignment create predictable patterns of pathology.

The heart emerges here not just as an organ, but as a developmental organiser — shaping flow, growth, and survival from the earliest weeks.

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