The philosophical question "can a leopard change his spots" is about whether a person can change something that is part of their base nature. Can I change a core behavior that has been a part of me since I was born or very young. If I was born with it like core personality trait or one that I grew into and held for my whole life, can it be changed?
I believe it can. I didn't always but through the work in personal and spiritual growth I have come to see a new character in myself. I have new core personality traits, ones that I am proud of.