UnHack with Drex DeFord

2 Minute Drill: AI Agents as the Next Insider Threat with Drex DeFord


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As healthcare organizations deploy AI agents across clinical, business, and research operations, we're creating a new class of insider threat—one that works 24/7, follows instructions perfectly, and moves at machine speed. Drexel explores why AI agents with tool access become de facto insiders and why we need clear boundaries, tight access controls, and human approval workflows before these powerful assistants cause unintended damage. The key insight: the moment an AI agent gets tools, it becomes an insider that must be governed like one.

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UnHack with Drex DeFordBy This Week Health