We welcome a true pioneer of psychedelics science, Dr. David Nichols, to the show.  The episode begins with panelists matching quotes about psychedelics to the famous person who gave the quote, and the substance they were referring to.  The pop literature segment explores a timeline of psychedelic events from 1990 - present.  Dr. Nichols provides a fascinating look into multiple landmark studies that were enabled by his lab’s willingness to synthesize the required psychedelic compounds.  For the peer reviewed segment the group assesses a recent publication about cutting edge methods for measuring the acute brain action of psychedelics.  This inspires a conversation about the practical utility of such tools in specific research areas and for driving the field forward.