Top Lung Health

#22 - Antifibrotic treatment in Pulmonary Fibrosis


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This episode is about antifibrotic treatments for pulmonary fibrosis. You can watch the video on my YouTube channel, here: https://youtu.be/5FHP_EoX1NM

Two medications are available (pirfenidone and nintedanib). These drugs may be prescribed for the following indications:

1. Idiopathic Pulmonary Fibrosis - both pirfenidone and nintedanib
Video about IPF: https://youtu.be/RNnVtCP3ae0
2. Progressive Fibrosing Interstitial Lung Disease (PF-ILD) or Progressive Pulmonary Fibrosis (PPF) - nintedanib only
3. Systemic sclerosis associated interstitial lung disease (SSc-ILD) - nintedanib only
Video about SSc-ILD: https://youtu.be/huecgJrXURI
These indications may change over time, and new medications may become approved. This information is valid as of April 2023. Please check with your doctor for accurate information in your case.
Antifibrotic medications do not "cure" fibrosis, but they can slow down the progression of the disease. This means that in the long run, being on the medication may be better than not having it. Lung function would be preserved for longer.
There are some potential side effects to antifibrotics that I discuss in the video.

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Top Lung HealthBy Dr. Stefan Cristian Stanel