Orders of Magnitude

22. What is Alzheimer's Disease?


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This week, we delve into the most common neurodegenerative disease: Alzheimer's.


References:

Stats on AD and Dementia: Monica Moore, M. S. G., Mirella Díaz-Santos, and Keith Vossel. "Alzheimer’s Association 2021 Facts and Figures Report."

Diagnosis of AD using PET scan: Chételat, Gaël, et al. "Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias." The Lancet Neurology 19.11 (2020): 951-962.

Amyloid Beta, the genetics of AD. Tanzi, Rudolph E. "The genetics of Alzheimer disease." Cold Spring Harbor perspectives in medicine 2.10 (2012): a006296.

APOE risk factor. Raber, Jacob, Yadong Huang, and J. Wesson Ashford. "ApoE genotype accounts for the vast majority of AD risk and AD pathology." Neurobiology of aging 25.5 (2004): 641-650.

Tau in Alzheimer's. Maccioni, Ricardo B., et al. "The revitalized tau hypothesis on Alzheimer's disease." Archives of medical research 41.3 (2010): 226-231.

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Orders of MagnitudeBy Science Communication Orders of Magnitude