TIKTok FAMOUS™: The Stories Behind the Scroll

26: Jackie Blankenship: XY Chromosomes, Mrs America Advocate


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In this episode of the TikTok FAMOUS™️ Podcast, host Meredyth Willits sits down with Jackie Blankenship, crowned Mrs. America 2022 and one of the boldest voices bringing awareness to what it means to be born intersex. Diagnosed with Complete Androgen Insensitivity Syndrome (CAIS), Jackie was born with XY chromosomes, but her body developed female because it couldn't respond to testosterone.

From growing up in silence to becoming a national pageant winner and social media educator, Jackie is turning curiosity into compassion and science into storytelling. This conversation sheds light on the gray areas of gender, identity, biology, and why representation matters more than ever.

Together, they unpack:

✅ What CAIS is and how it affects the body ✅ Why Jackie's natural hormone production came from internal testes ✅ The pressure to keep her diagnosis secret and the emotional toll ✅ How surgery, shame, and misinformation shaped her early life ✅ Her decision to speak out and use pageantry as a platform

Jackie also opens up about…

✨ Why removing her testes at 15 forced her into early menopause ✨ The trauma older generations with CAIS still carry ✨ How TikTok gave her the power to educate, advocate, and relate ✨ Her journey to motherhood through donor eggs and surrogacy ✨ The importance of accurate representation beyond extremes

Whether you've never heard of intersex before or you've been afraid to ask questions, this episode invites you to learn, listen, and expand your understanding of what it really means to live in the in-between. Jackie shows us that being different isn't something to fix, it's something to embrace.

00:00 Welcome to the TikTok FAMOUS™️ Podcast. Meet Jackie Blankenship 00:45 Diagnosed with CAIS at age 4 and born with XY chromosomes 03:00 Why her body developed female and the role of testosterone 05:30 Family history, generational trauma, and medical decisions 08:15 Undergoing surgery at 15 and forced into early menopause 11:20 Discovering the estrogen conversion process in her body 13:00 Secrets, silence, and being told to keep it private 15:30 Dating, disclosure, and why friendship came first 18:00 How she told her now-husband and built a family 20:00 Pageantry and using Mrs. America as a platform 22:30 Reactions from fellow contestants and production 25:00 Being hyper-feminine doesn't make you more valid 27:30 TikTok virality and her signature "Let's talk about it" videos 30:00 Why representation matters for ALL intersex people 33:00 The science of gender, testosterone, and chromosome variations 35:30 Children's books, education, and raising her daughter 38:00 The real dangers of politicizing identity and erasing stories 41:00 Advocating without shame and speaking for the unheard 43:00 Book bans, inclusion, and letting kids see themselves 46:00 The 40+ variations of intersex most people never hear about 48:00 Her message to parents, teachers, and listeners everywhere 50:00 Final thoughts. Belonging, biology, and building a more compassionate world

🔗 Connect with Jackie Blankenship ✨ TikTok: @mrsjackieblanks ✨ Instagram: @mrsjackieblanks ✨ Facebook: Jackie Blankenship

🔗 Connect with Meredyth Willits & the TikTok FAMOUS™️ Podcast ✨ Facebook: Meredyth Willits ✨ Instagram: @meredyth_willits ✨ TikTok: @meredyth_with_a_why ✨ YouTube: TikTok FAMOUS™️ Podcast | Meredyth Willits 🎙️ Hosted by Meredyth Willits, where viral fame meets raw reality. Subscribe, review, and stay tuned for more real talk from the creators who move us.

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TIKTok FAMOUS™: The Stories Behind the ScrollBy Meredyth Willits