Infectiously SMART

#3 Antibiotic Dilemmas – When to De-escalate & When to Double Down


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📌 Why This? Many clinicians struggle with antimicrobial stewardship and when to step down therapy.


💊 In this episode, we’ll cover:When to STOP broad-spectrum antibiotics (when NOT to!)How long should you treat? 5, 7, or 14 days?A real-life case of de-escalation

🚨 You started piperacillin-tazobactam for pneumonia, but now cultures show Klebsiella pneumoniae.

Do you step down to ceftriaxone or keep the broad coverage?

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Infectiously SMARTBy Dr. Jean Capulong Linsao