Forget all the discussion about which celebrities are taking Ozempic and whether it’s cheating, one thing seems clear - it works!

But how? Join our mother and daughter duo as they talk about how our body, Ozempic and 3lbs of microscopic bacteria work together to achieve often-dramatic weight loss.

0:00 Introduction

2:00 Why do we feel hungry, what interacting processes are occurring in our gut and brain to make us desperate for dinner?

Hungry for more? Try these: https://onlinelibrary.wiley.com/doi/epdf/10.1002/ueg2.12097 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588461/

4:45 What is Glucagon-like peptide 1 (GLP-1) and what does it do?

Want to dive a little deeper into GLP-1? Read this: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8736331/

8:25 Why is GLP-1 important to the Ozempic story?

10:20 Is GLP-1 the only thing we need to consider when thinking about hunger? What about other chemical signals including ghrelin, leptin and CCK?

Fascinated by ghrelin? Here’s more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049314/#:~:text=Ghrelin%20is%20a%20multifaceted%20gut,as%20the%20%E2%80%9Chunger%20hormone%E2%80%9D.

For some sweet info on how our plasma glucose (blood sugar) makes us feel full or hungry: https://www.nature.com/articles/s42255-021-00383-x

12:20 What is the gut biome?

13:30 How might our gut biome affect our natural production of GLP-1 and our weight?

Spellbound by the relationship between GLP-1 and bacteria? Digest this:

https://www.nature.com/articles/s41598-020-61112-0

15:30 Why do we always think of bacteria as the bad guys? A story of lovable bacteria.

18:00 When you understand how Ozempic works, its side-effects make perfect sense!

19:55 Should we be concerned about Ozempic and long-term side-effects?

23:10 The team signs off, stay curious everyone