Description: Join us for a fascinating deep dive into the intricate relationship between cannabinoids and TRP channels, particularly TRPV1 and TRPM8. Dr. Rafael Mechoulam's groundbreaking research laid the foundation for our understanding of the endocannabinoid system, but we're now discovering an exciting new frontier beyond the classical CB1 and CB2 receptors.

Learn how TRPV1 channels respond to heat and spicy compounds like capsaicin, while TRPM8 channels mediate our sensation of cold and menthol. We'll explore how cannabinoids like CBD can interact with these channels, potentially opening new avenues for pain management and therapeutic applications. From molecular signaling cascades to practical implications for drug development, this episode breaks down complex concepts into digestible insights for both science enthusiasts and healthcare professionals.