This podcast episode explores the complex challenges of scaling up production of cannabinoid and psychedelic APIs (Active Pharmaceutical Ingredients) from laboratory to commercial scale. Using Watson's Pharmaceutical Process Development as a guide, the discussion covers key aspects including:

- Balancing yield maximization, cost minimization, and waste management while maintaining product safety and efficacy

- The differences between batch and continuous processing methods

- Specific challenges with sensitive compounds from natural sources, including quality control and contamination prevention

- Environmental considerations and sustainable production methods, including green chemistry approaches

The episode provides detailed insights into both traditional extraction methods and emerging synthetic approaches for producing these therapeutic compounds.