On this episode of our Health Update Series in collaboration with the World Health Organization, we focus on the increasing risk and historical trends of flooding in Upper Nile, highlighting its impact on population displacement, public health, and health service delivery. Director General in the State Ministry of Health, Dr. Isaac Kwongo Ogilo and World Health Health Organisation's State Coordinator, Dr Emmanuel Timothy Thwol speak on the health response that includes preparedness planning, logistics, workforce mobilisation, disease surveillance, and infection prevention. They detail the coordination among the State Ministry of Health, WHO, and partners through health cluster mechanisms, focusing on continuity of care, infrastructure resilience, community engagement, and support for vulnerable groups.