October in MedTech was wild billion-dollar deals, bold spinouts, and the future of incision-free surgery.

Omar Khateeb and Nicholas Talamantes, Senior Director of Market Intelligence at Life Science Intelligence break down how Boston Scientific, J&J, and Stryker are reshaping the field  plus which startups made LSI’s Hot 25 list.

Listen in for the market moves, investor insights, and tech shifts defining healthcare’s next decade.

Episode Breakdown

00:00:00  Cold open & state of MedTech: hardware, AI, incisionless surgery

00:00:53  Host banter October, pumpkin patch moment

00:01:29  Quick banter return / show intro

00:01:38  Welcome back this month in MedTech overview (LSI + Compass)

00:05:45  Boston Scientific acquires Nalu (neuromodulation trend)

00:15:40  J&J spins out DePuy (orthopedics divestiture explained)

00:15:42  DePuy robotics market positioning & competition

00:17:24  Strategic implications mini-strategics and M&A dynamics

00:17:57  Orthopedics robotics strategy & what to watch (Stryker, Mako)

00:26:26  Q3 medtech funding recap fewer deals, bigger rounds

00:26:26  Funding trends: late-stage up, early-stage down; investor behavior

00:35:34  LSI Q4 Hot 25 intro what the list means and where to find it

00:35:55  How the Hot 25 are scored (funding, team, market, tech diff)

00:36:41  Hot 25 highlights Setpoint Medical (vagus nerve bioelectric)

00:36:41  Hot 25 highlights AI Doc (AI imaging triage)

00:36:41  Hot 25 highlights BioLink (needle-free wearable biosensor)

00:40:43  Hosts’ favorite picks why BioLink and Galvanize stand out

00:43:40  Galvanize deep dive focus shift to pulmonary & tumors

00:47:48  Deals of the month intro notable rounds & why they matter

00:47:48  Coal Mine raises $60M noninvasive brain monitoring (EU)

00:50:46  Out of Core $75M extravascular rhythm management (CRM)

00:50:46  DermaSensor $16M Series B handheld AI skin cancer detection

00:52:52  Petal Surgical $10M incisionless surgery / histotripsy space

00:55:41  Why incisionless surgery matters histotripsy context & roadmap

00:55:45  LSI conference & keynote preview (Petal + Fred Moll)

00:57:30  October recap: consolidation, robotics, neuromodulation, capital

01:00:56  Compass plug how the platform helps investors & founders

01:05:24  Final takeaways: partnerships, leverage, and early-market strategy

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