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334.How Your Microbiome Controls Your Health with Leo Grady, Founder and CEO of Jona
Could your gut be the key to solving chronic fatigue, autoimmune issues, or even mental health? Leo Grady, Founder and CEO of Jona, joins the show to explain how AI is unlocking the secrets of the microbiome one stool sample at a time.
From fecal transplants to personalized diet plans, learn how deep sequencing and transparent science are changing healthcare without the guesswork.
Stream the episode and take control of your health from the inside out.
Episode Breakdown
0:00 – Why the gut microbiome is the missing key to modern medicine
1:00 – Meet Leo Grady, Founder and CEO of Jona: from AI in radiology to founding Jona Health
2:30 – The moment AI met biology: how data revealed the gut’s hidden power
4:00 – Why chronic disease, obesity, and inflammation start in the microbiome
6:00 – Building an AI model for the human gut: challenges and breakthroughs
8:30 – From Siemens Healthineers to Jona: Leo’s leap into microbiome medicine
10:00 – The science behind poop transplants and what they teach us
12:00 – How diet, stress, and sleep rewrite your gut ecosystem
14:30 – Using sequencing data and AI to personalize nutrition
17:00 – What a Jona test actually measures and how results are delivered
19:00 – Breaking down the gut report: good vs. bad bacteria explained
21:00 – How AI analyzes 2,000+ new gut studies each month
23:00 – Key biomarkers linked to fatigue, weight gain, and brain fog
25:00 – Microbiome diversity: why it matters more than calories
27:00 – The gut-brain connection: mood, dopamine, and serotonin
29:00 – Why most gut testing companies get the science wrong
31:00 – Lessons learned from the uBiome collapse and regaining trust
33:00 – Building a medical-grade company in the consumer health space
35:00 – The new wave of evidence-based biohacking
37:00 – AI vs. traditional medicine: merging two worlds of care
39:00 – Surprising discoveries from Jona’s real-world patient data
41:00 – How antibiotics, fasting, and fiber affect the microbiome
43:00 – The gut as your body’s sensory organ: interpreting internal signals
45:00 – Top foods that rebuild the microbiome naturally
47:00 – How wearables and gut data together unlock holistic health
49:00 – Leo’s daily health stack: protein, recovery, and AI tracking
51:00 – Final insights: why the microbiome revolution is just beginning
52:00 – Outro: subscribe, share, and take control of your gut health
Are you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to GrowMyMedtech.com to book time for a free analysis.
Subscribe to our Youtube Channel
https://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfg
Subscribe to our LinkedIn Newsletter
https://www.stateofmedtechpodcast.com/
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#GutHealth #Microbiome #Biohacking #MedTech #HealthTech
View all episodes
By State of MedtechCould your gut be the key to solving chronic fatigue, autoimmune issues, or even mental health? Leo Grady, Founder and CEO of Jona, joins the show to explain how AI is unlocking the secrets of the microbiome one stool sample at a time.
From fecal transplants to personalized diet plans, learn how deep sequencing and transparent science are changing healthcare without the guesswork.
Stream the episode and take control of your health from the inside out.
Episode Breakdown
0:00 – Why the gut microbiome is the missing key to modern medicine
1:00 – Meet Leo Grady, Founder and CEO of Jona: from AI in radiology to founding Jona Health
2:30 – The moment AI met biology: how data revealed the gut’s hidden power
4:00 – Why chronic disease, obesity, and inflammation start in the microbiome
6:00 – Building an AI model for the human gut: challenges and breakthroughs
8:30 – From Siemens Healthineers to Jona: Leo’s leap into microbiome medicine
10:00 – The science behind poop transplants and what they teach us
12:00 – How diet, stress, and sleep rewrite your gut ecosystem
14:30 – Using sequencing data and AI to personalize nutrition
17:00 – What a Jona test actually measures and how results are delivered
19:00 – Breaking down the gut report: good vs. bad bacteria explained
21:00 – How AI analyzes 2,000+ new gut studies each month
23:00 – Key biomarkers linked to fatigue, weight gain, and brain fog
25:00 – Microbiome diversity: why it matters more than calories
27:00 – The gut-brain connection: mood, dopamine, and serotonin
29:00 – Why most gut testing companies get the science wrong
31:00 – Lessons learned from the uBiome collapse and regaining trust
33:00 – Building a medical-grade company in the consumer health space
35:00 – The new wave of evidence-based biohacking
37:00 – AI vs. traditional medicine: merging two worlds of care
39:00 – Surprising discoveries from Jona’s real-world patient data
41:00 – How antibiotics, fasting, and fiber affect the microbiome
43:00 – The gut as your body’s sensory organ: interpreting internal signals
45:00 – Top foods that rebuild the microbiome naturally
47:00 – How wearables and gut data together unlock holistic health
49:00 – Leo’s daily health stack: protein, recovery, and AI tracking
51:00 – Final insights: why the microbiome revolution is just beginning
52:00 – Outro: subscribe, share, and take control of your gut health
Are you a medtech CEO in need of some marketing help attracting investors, growing sales pipeline, and more? Go to GrowMyMedtech.com to book time for a free analysis.
Subscribe to our Youtube Channel
https://www.youtube.com/channel/UCGpL_rGt1LQJwinMq_K7gfg
Subscribe to our LinkedIn Newsletter
https://www.stateofmedtechpodcast.com/
Follow The State of MedTech on
LinkedIn https://www.linkedin.com/company/thestateofmedtech
Instagram https://www.instagram.com/stateofmedtech/
TikTok https://www.tiktok.com/@stateofmedtech
X https://twitter.com/StateofMedTech
Facebook https://www.facebook.com/stateofmedtech/
Follow Omar M. Khateeb on
LinkedIn https://www.linkedin.com/in/okhateeb/
Instagram https://www.instagram.com/omar.m.khateeb/
TikTok https://www.tiktok.com/@omarkhateebofficial
X https://twitter.com/OmarMKhateeb
Facebook https://www.facebook.com/OmarMKhateeb/
#GutHealth #Microbiome #Biohacking #MedTech #HealthTech