Web3 with Sam Kamani

353: How to win DeFi on Hyperliquid with guest speaker João Nuno Simões from Hyperwave


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I sit down with João Simoes — a true builder, repeat founder, and one of the sharpest BD minds in Web3. We go deep on his journey from running Portugal’s first Bitcoin mining company to building and exiting a restaking startup and now co‑founding Hyperwave on Hyperliquid. We unpack why Hyperliquid is thriving, what real community‑driven growth looks like, and the problem Hyperwave is solving with standout DeFi vaults and future payment rails. We also dive into market trends, real‑world events shaping crypto, and practical advice for builders in 2026. Honest, real and full of insights.

🔑 Key Learnings & Time Stamps

  • 00:00 – Intro & What to Expect
  • 01:48 – João’s Origin Story: From Bitcoin Mining to Web3
  • 07:20 – Why Hyperliquid Has Succeeded vs. Other Projects
  • 12:51 – What Hyperwave Is Building & Why It Matters
  • 16:12 – How Hyperwave Vaults Deliver High Stable Yields
  • 18:39 – The Power of People, Networks & BD in Crypto
  • 25:09 – The Web3 Event Landscape & Community Dynamics
  • 31:45 – Vault Mechanics, Token Strategy & Integrations
  • 34:38 – João’s 2026 Outlook on Markets & Crypto Trends
  • 48:36 – Advice for Builders & Founders in DeFi
  • 52:20 – What Hyperwave Is Looking For Now





https://discord.gg/hyperwave






⚠️ Disclaimer

Nothing mentioned in this podcast is investment advice and please do your own research.


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Web3 with Sam KamaniBy Sam Kamani