In this interview, we discuss the ethics of normothermic regional perfusion. NRP involves using a machine to pass blood through organs in a person’s body after the heart has irreversibly stopped beating. Vessels are clamped during this procedure to prevent blood flow to the brain. As a surgical procedure NRP shows a positive impact on utility by reducing non-use of organs without negatively impacting patient outcomes. However, the fact that NRP involves recirculation after declaration of death by circulatory criteria raises concerns about compliance with the Dead Donor Rule and nonmaleficence (do no harm).