San Francisco leads this series 76-68-3 overall and these NFC West rivals are tied in the postseason 1-1, the most recent postseason game very recent and memorable. Jimmy G vs. Matthew Stafford yet again. The 49ers have dominated the Rams in the regular season. Winning 9 regular season games in a row what will happen this Sunday? It's the final regular season meeting until next year or possibly the tournament in January 2023!