Discover with Dr. Dan | Proactive Health

#52: Berberine | Reduce the Effects of Metabolic Syndrome, PCOS, and Diarrhea


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Today we’re going to talk about the amazing bioactive compound, berberine. Berberine has been used in traditional Chinese medicine and ayurveda for more than 1500 years and is found in many different plants, among such are Berberis Vulgaris, Coptus Chenensus, and Berberidis Cortex. Berberine belongs to a class of molecules called Isoquinoline Alkaloids. It’s a flat molecule, it’s planar, and it’s aeromatic, meaning that the electrons can move together in a conjugated system. Berberine has been found to regulate insulin levels, as well as change the composition of the 10 trillion bacterial cells that live in our gut. It helps with overall cholesterol levels as well as overall heart health, and can even reduce chances of polycystic ovarian syndrome, a frequent reproductive and metabolic disorder associated with insulin resistance, increasing birth rates.

Physical characteristics 2:04
Health benefits and metabolic syndrome 3:08
Meta analysis on berberine 5:10
Insulin 8:52
PCOS 13:26
Preventing acute diarrhea 16:14
Why berberine is good 17:10

“There’s actually 5 criteria for metabolic syndrome. Number one is elevated waist circumference. Number two is high fasting blood glucose levels. Number three is high triglycerides. Number four is low HDL cholesterol, and number five is high blood pressure. These are the 5 criteria and a person has metabolic syndrome if they have at least 3 of these 5 criteria.” 3:59

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Discover with Dr. Dan | Proactive HealthBy Dr. Dan Gubler