Think Twice Podcast

56 : A Psychedelic Reboot : Rewiring the Brain After Concussions


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A concussion isn't just a bump on the head; it disrupts entire networks and can have long term implications when ignored. Unfortunately, even with advances in modern neuroscience, recovery is difficult and sometimes ineffective. In this episode, we discuss how psychedelics may enhance neuroplasticity and what that could mean for concussion recovery with Dylan, a graduate student studying the intersection of psychedelics and traumatic brain injuries. We dive into the biological mechanisms behind neuroplasticity, why concussions disrupt it, and how psychedelic compounds are being investigated as potential tools to support the brain’s adaptive processes. We also discuss personal experiences with concussions, current research limitations, and what the next generation of studies aims to uncover.
Dylan Graff is a second-year master's student at Queen’s University Centre for Neuroscience Studies, where he works under the supervision of Dr. Douglas James Cook. His research focuses on using advanced neuroimaging methods, particularly resting-state fMRI, to understand how mild traumatic brain injuries affect brain connectivity and network function. Driven by a strong interest in both brain injury and mental health, Dylan’s work also examines the therapeutic potential of psychedelic-assisted therapies. He aims to bridge findings from psychedelic research in mood disorders with neuroimaging studies in brain injury, exploring whether these emerging treatments may help address persisting symptoms after concussion.
Authors: Eve Racette, Golnar Taheri
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Disclaimer: Think Twice is a podcast for general information and entertainment purposes only. The content discussed in the episodes does not reflect the views of the podcast committee members or any institution they are affiliated with. The use of the information presented in this podcast is at the user’s own risk and is not intended to replace professional healthcare services.
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