Sit. Stay. Learn. with Dr. Adrienne Wright

6. Switching Species: What a Human CKD Pilot Teaches Vet Med about Adipose MSCs


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This week, we’re exploring a fascinating human pilot study with powerful takeaways for veterinary medicine. The research, “Adipose tissue-derived mesenchymal stromal cells for treating chronic kidney disease: A pilot study assessing safety and clinical feasibility” (Villanueva et al., 2019), examined how stem cells may support kidney function in people with chronic kidney disease (CKD). Results showed improved proteinuria and slower disease progression in most patients—without adverse effects. These findings mirror what’s been observed in veterinary cases using mesenchymal stromal cells (MSCs), where pets often show better energy, appetite, and stability even when lab results shift modestly. As CKD remains one of the most common conditions in older dogs and cats, this study highlights how regenerative therapies could play a larger role in managing long-term kidney health.

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Sit. Stay. Learn. with Dr. Adrienne WrightBy Dr. Adrienne Wright