the bioinformatics chat

#64 Enformer: predicting gene expression from sequence with Žiga Avsec


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In this episode, Jacob Schreiber interviews Žiga Avsec about

a recently released model, Enformer. Their discussion begins with life
differences between academia and industry, specifically about how research
is conducted in the two settings. Then, they discuss the Enformer model,
how it builds on previous work, and the potential that models like it have
for genomics research in the future. Finally, they have a high-level discussion
on the state of modern deep learning libraries and which ones they use in their
day-to-day developing.

Links:

  • Effective gene expression prediction from sequence by integrating long-range interactions (Žiga Avsec, Vikram Agarwal, Daniel Visentin, Joseph R. Ledsam, Agnieszka Grabska-Barwinska, Kyle R. Taylor, Yannis Assael, John Jumper, Pushmeet Kohli & David R. Kelley )
  • DeepMind Blog Post (Žiga Avsec)
  • If you enjoyed this episode, please consider supporting the podcast on Patreon.

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