The Rest is Health

#65 - Dr. Mark Mattson | Neuroscience, Intermittent Fasting, and Brain Health


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Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they interview Dr. Mark Mattson, one of the world’s leading neuroscientists and a pioneer in the study of aging, brain health, and neurodegenerative diseases. Dr. Mattson is Chief of the Laboratory of Neurosciences at the National Institute on Aging and Professor of Neuroscience at Johns Hopkins University. With over 340 research articles and decades of groundbreaking work, he is widely recognized for his contributions to understanding neuronal plasticity, Alzheimer’s disease, and the powerful role of lifestyle in brain health.

In this episode, Dr. Mattson shares insights from his pioneering research on intermittent fasting and its neuroprotective effects, explaining how metabolic switching influences brain function, resilience, and longevity. He also discusses the cellular and molecular mechanisms underlying neuroplasticity and aging, highlighting how dietary and lifestyle interventions can prevent or delay neurodegenerative disorders.

Listeners will gain a deeper understanding of how fasting, exercise, and stress adaptation shape brain health across the lifespan. Dr. Mattson’s expertise bridges cutting-edge science with practical strategies, offering a hopeful vision for preventing cognitive decline and supporting healthy aging.

Dr. Mark Mattson isn't on social media but encourages reaching out for any questions directly to his email which is:

[email protected]

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The Rest is HealthBy Dr. Sandra Cammarata And Dr. Giovanni Campanile

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