the bioinformatics chat

#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus

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In this episode,

David Dylus talks about
Read2Tree,
a tool that builds alignment matrices and phylogenetic trees from raw
sequencing reads.
By leveraging the database of orthologous genes called OMA, Read2Tree bypasses traditional, time-consuming steps such as genome assembly, annotation and all-versus-all sequence comparisons.

Links:

  • Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
    • (David Dylus, Adrian Altenhoff, Sina Majidian, Fritz J. Sedlazeck, Christophe Dessimoz)
  • Background story
  • Read2Tree on GitHub
  • OMA browser
  • The Guardian’s podcast about Victoria Amelina and Volodymyr Vakulenko

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