Ever wonder what it takes to excel as a leader when your path is unconventional?

In this episode, Nicole McMackin interviews Carmella Cassetta, an accomplished healthcare CIO, to explore the realities behind career advancement, overcoming internal challenges, and the true meaning of giving back. Carmella’s journey from humble beginnings challenges the idea that success requires a traditional background, a linear trajectory, or permission from gatekeepers.

If you are seeking inspiration to move beyond self-doubt and embrace new perspectives on leadership in technology, healthcare, and beyond, this conversation offers valuable insights. Discover the mindset shifts that drive impactful leadership because the most important lessons are not taught, but revealed.

Listen now to join the discussion.

Timestamped Highlights

[00:02:22] – A murder mystery author puts Carmella’s name in his novel… what did this teach her about leaving an impression?

[00:04:49] – Grit, scarcity, and invisible obstacles: The untold story behind Carmella’s tough Connecticut upbringing—and the power of “happy, but challenging.”

[00:13:47] – “You can’t, you can’t, you can’t…” How to flip rejection and make doubters your biggest fans

[00:17:19] – Starting in retail, pivoting to technology: The surprising ‘aha’ moments that nobody saw coming

[00:23:33] – The hidden technique that gets projects approved… and why “the meeting before the meeting” is the real boardroom superpower

[00:28:02] – Turning critics into advocates: How Carmella wins over the toughest personalities (and you can, too)

[00:36:14] – Facing imposter syndrome, even at the top: Real talk about self-worth and how high-achievers shatter insecurity

[00:46:00] – 4 pillars most leaders overlook: Why being current, mastering business, and building relationships spell victory

About The Guest

Carmella Cassetta is the Chief Information Officer (CIO) at Hoag Memorial Hospital Presbyterian, one of Southern California’s most respected healthcare institutions. With more than two decades in technology leadership, Carmella’s reputation is built on relentless advocacy for women, pioneering operational transformation, and her rare blend of compassion and business grit. She’s an active board member for the Association of Women in Technology, sits on multiple leadership groups, and is a sought-after influencer in both healthcare and tech.

🔗 LinkedIn | Website

Mentioned Resources

• Hoag Memorial Hospital Presbyterian
• Association of Women in Technology (AWT)
• SIM Southern California
• University of Connecticut
• StrengthsFinder (book)
• Barnes & Noble
• Brooks Brothers
• Toastmasters
• Ruth Bader Ginsburg (documentary)
• Margaret Thatcher
• Kate Middleton (Princess of Wales)

Important Links

• Irvine Technology Corporation
• Nicole McMackin on LinkedIn

Elevate Your Career is an original podcast hosted by Nicole McMackin. Production and editing by Podcast Your Brand.