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Hi, This Week in Medicine, we will be discussing
First we will be discussing articles in New England Journal of Medicine
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes
Ciprofloxacin versus Aminoglycoside–Ciprofloxacin for Bubonic Plague
Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer
First-Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer
Journal of American Medical Association
Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours
Annals of Internal Medicine
Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain: A Randomized Controlled Trial
JAMA oncology
Modeling Population-Level Impacts of Cell-Free DNA Screening for Colorectal Cancer in Canada
Journal of Clinical Oncology
Randomized Phase II Study of Concurrent Versus Sequential Pembrolizumab in Combination With Chemoradiation in Locally Advanced Head and Neck Cancer
journal of Hepatology
A phase IIb randomised-controlled trial of the FFAR1/FFAR4 agonist icosabutate in MASH
Gastroenterology
Risk of Gastric Adenocarcinoma After Eradication of Helicobacter pylori
Clinical Gastroenterology
Lymphocytic Esophagitis: A Histologic Pattern of Various Underlying Disorders
Clinical Infectious Diseases
Target Trial Emulation of SARS-CoV-2 Infection Versus No Infection and Risk of Post–COVID-19 Conditions in the Omicron Variant Versus Prior Eras
Rheumatology
Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease
Circulation
Abelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation on Antiplatelet Therapy: A Prespecified Analysis of the AZALEA-TIMI 71 Trial
Journals of the American College of Cardiology
Using Compression Stockings to Prevent Recurrence of Vasovagal Syncope: A Randomized Sham-Controlled Trial
JAMA Cardiology
Cumulative Life’s Essential 8 Scores and Cardiovascular Disease Risk
Journal of Clinical Endocrinology & Metabolism
Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022
Diabetes care
Lack of Validity of the Glucose Management Indicator in Type 1 Diabetes in Pregnancy
Neurology
Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study
The American Journal of Respiratory and Critical Care Medicine
Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4)
Clinical Journal of American Society of Nephrology
Sodium-Glucose Cotransporter-2 Inhibitor Therapy and Longitudinal Changes in Kidney Function among Veterans with Autosomal Dominant Polycystic Kidney Disease
Here are the articles from Kidney International reports
A Systematic Review of Treatment for Acute Interstitial Nephritis
By A.I.O.Hi, This Week in Medicine, we will be discussing
First we will be discussing articles in New England Journal of Medicine
Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes
Ciprofloxacin versus Aminoglycoside–Ciprofloxacin for Bubonic Plague
Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer
First-Line Camizestrant for Emerging ESR1-Mutated Advanced Breast Cancer
Journal of American Medical Association
Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours
Annals of Internal Medicine
Efficacy of a Very-Low-Calorie Weight Loss Diet Plus Exercise Compared With Exercise Alone on Hip Osteoarthritis Pain: A Randomized Controlled Trial
JAMA oncology
Modeling Population-Level Impacts of Cell-Free DNA Screening for Colorectal Cancer in Canada
Journal of Clinical Oncology
Randomized Phase II Study of Concurrent Versus Sequential Pembrolizumab in Combination With Chemoradiation in Locally Advanced Head and Neck Cancer
journal of Hepatology
A phase IIb randomised-controlled trial of the FFAR1/FFAR4 agonist icosabutate in MASH
Gastroenterology
Risk of Gastric Adenocarcinoma After Eradication of Helicobacter pylori
Clinical Gastroenterology
Lymphocytic Esophagitis: A Histologic Pattern of Various Underlying Disorders
Clinical Infectious Diseases
Target Trial Emulation of SARS-CoV-2 Infection Versus No Infection and Risk of Post–COVID-19 Conditions in the Omicron Variant Versus Prior Eras
Rheumatology
Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease
Circulation
Abelacimab Versus Rivaroxaban in Patients With Atrial Fibrillation on Antiplatelet Therapy: A Prespecified Analysis of the AZALEA-TIMI 71 Trial
Journals of the American College of Cardiology
Using Compression Stockings to Prevent Recurrence of Vasovagal Syncope: A Randomized Sham-Controlled Trial
JAMA Cardiology
Cumulative Life’s Essential 8 Scores and Cardiovascular Disease Risk
Journal of Clinical Endocrinology & Metabolism
Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022
Diabetes care
Lack of Validity of the Glucose Management Indicator in Type 1 Diabetes in Pregnancy
Neurology
Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study
The American Journal of Respiratory and Critical Care Medicine
Endotypes of Pseudomonas aeruginosa Infection in Bronchiectasis Are Associated with Inhaled Antibiotic Response: Results from Two Randomized, Double-Blind, Placebo-controlled Phase III Trials (ORBIT 3 and ORBIT 4)
Clinical Journal of American Society of Nephrology
Sodium-Glucose Cotransporter-2 Inhibitor Therapy and Longitudinal Changes in Kidney Function among Veterans with Autosomal Dominant Polycystic Kidney Disease
Here are the articles from Kidney International reports
A Systematic Review of Treatment for Acute Interstitial Nephritis