"One drug, three doses, one test.” In this episode of 'What's the Proof?', we are joined by our guest, Dr. Bobby Levy, who will be discussing the application of buprenorphine-naloxone in the treatment of opioid use disorder. Discover how personal experiences led Dr. Levy to become a passionate advocate for integrating opioid use disorder treatment into primary care.  Gain insights into the robust evidence supporting the use of buprenorphine, its practical dosing and initiation, and Dr. Levy's compelling counterpoints to common criticisms. This episode offers a unique perspective for any physician keen on confronting the opioid epidemic. Listen in and find out how you can make a life-saving impact in your community.

Episode Outline:

• Opening remarks - 00:35
• Introducing Dr. Levy and his journey to OBOT - 02:31
• The role of Primary Care Providers in OBOT - 09:42
• Evidence supporting buprenorphine-naloxone - 12:46
• Debunking the myth of "trading one addiction for another" - 20:52
• Harm reduction model - 22:48
• Potential challenges and downsides - 24:48
• Dosing and initiation - 28:00
• Key takeaways from interview - 33:26
• Host reflections and closing - 35:46

Episode Links:

• Questions for Dr. Levy - [email protected]
• NEJM RCT - https://pubmed.ncbi.nlm.nih.gov/12954743/
• Efficacy of Bup in primary care - https://pubmed.ncbi.nlm.nih.gov/19553061/
• Cochrane Review - https://pubmed.ncbi.nlm.nih.gov/15266465/
• BMJ Cohort Study on mortality - https://pubmed.ncbi.nlm.nih.gov/32234712/
• All-cause mortality benefit- https://pubmed.ncbi.nlm.nih.gov/34076676/

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Credits:

• Hosts: Bobby Scott, MD, FAAFP; Sandy Robertson, PharmD; Dawn Caviness, MD, BSN
• Production & Cover Art: Bobby Scott, MD, FAAFP
• Music: Twisterium, MondayHopes, Muzaproduction, and SergeQuadrado from Pixabay