Sentience

8. Farah Lubin, PhD on epigenetics and the brain


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In this episode, I sit down with Dr. Farah Lubin, a neuroscientist from the University of Alabama at Birmingham, to explore the fascinating world of epigenetics in the brain. Dr. Lubin shares her groundbreaking research on how gene expression can influence memory formation and neurological disorders like epilepsy. We also discuss how understanding these mechanisms could lead to novel therapies, along with the transformative power of epigenetics in brain science. Follow along as Dr. Lubin walks us through her unique career journey and sheds light on the evolving field of neuroepigenetics.


Timestamps:

(00:00) - Introduction to Dr. Farah Lubin and her research on epigenetics
(06:00) - Epigenetic mechanisms: DNA methylation and histone modifications
(09:00) - Epigenetics and brain plasticity in memory and learning
(12:00) - The role of DNA methylation in gene expression and memory
(18:00) - Epigenetics and the consolidation of long-term fear memories
(25:00) - How brain-derived neurotrophic factor (BDNF) is influenced by epigenetics
(30:00) - The role of epigenetics in epilepsy development and resilience
(35:00) - Methionine supplementation and its potential impact on memory
(40:00) - The importance of environmental influences on the epigenome
(46:00) - Future directions in epigenetics: new sequencing technologies
(52:00) - Funding challenges in neuroscience research and the value of basic science
(56:00) - Advice for students interested in neuroscience and epigenetics

...more
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SentienceBy Daniel Toker