We cover the biology of pancreatic cancer and why it's one of the most lethal diagnoses in medicine, what stage 4 actually means, and where the science is headed with KRAS inhibitors, BRCA2 targeted therapies, and clinical trials. Then we go deeper into something I think most people avoid: the moment you're born is the moment you start dying. Telomere biology, cellular senescence, Heidegger's "beings-toward-death," memento mori, mono no aware, Buddhist impermanence, and Irvin Yalom's awakening experiences. And finally, what all of this means for how we actually live; Bronnie Ware's regrets of the dying, the Blue Zones research on longevity and belonging, Maslow on self-actualization, Viktor Frankl on meaning, and Seneca on time.

We are all dead men walking. The only real question is what we do with the time.

Regrets of the dying: https://open.spotify.com/episode/07Y5iqmIoOvSgI8kR4hLMV

Blue Zones: https://open.spotify.com/episode/7zTJuHOlfzue7PTsZ0u1xK

Self-Actualization: https://open.spotify.com/episode/2JjRwLjNm8w6U7krHLkDb3

93-Year-Old's Advice on Life: https://open.spotify.com/episode/0Vf7rlzQzGIbgQoqRyktIr

Find Your Purpose: https://open.spotify.com/episode/6gP7Jhy88sL87qWQl3TuFL