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83: Expanding the DED Toolkit: Cold-Sensitive Approaches to Tear Regulation


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Episode Description 

In this podcast, experts Janelle L. Davison, OD; Cecelia Koetting, OD, FAAO, DipABO; and Cory J. Lappin, OD, MS, FAAO; discuss neuromodulation as a treatment modality for dry eye disease, focusing on a novel thermoregulatory therapy.

Learning Objectives 

Upon successful completion of this activity, you should be better prepared to:

  • Describe the neural network that monitors the ocular surface environment and regulates tear secretion
  • Assess the mechanisms of action of neuromodulation therapeutics in dry eye disease (DED)
  • Evaluate current and emerging therapeutics for DED
  • Identify clinical applications and patient selection for neuromodulation therapies in DED
  • Acknowledgment of Educational Grant Support

    This activity is supported by an educational grant from Alcon Vision, Inc.

    Faculty:

    Janelle L. Davison, OD

    Owner and Clinical Director
    Brilliant Eyes Vision Center
    Visionary Dry Eye Institute
    Smyrna, GA

    Disclosures: Janelle L. Davison, OD, has no relevant financial relationships with ineligible companies.

    Cecelia Koetting, OD, FAAO, DipABO

    Assistant Professor
    Department of Ophthalmology
    University of Colorado School of Medicine
    Denver, CO

    Disclosures: Advisor, Consultant, Speaker, Honoraria Recipient: AbbVie/Allergan, Alcon Inc, Bausch + Lomb, Dompé, Harrow, Movu, Myze, Orasis Pharmaceuticals, Tarsus Pharmaceuticals, Topcon, Viatris Inc, Visus; Grant/Research Funding: Kala Bio

    Cory J. Lappin, OD, MS, FAAO

    Founder
    The Dry Eye Center of Ohio
    Cincinnati, OH

    Disclosures: Advisory Board, Consultant, Speaker: Alcon Inc; Barti; Bausch + Lomb; Bruder Healthcare and M&S Technologies (Hilco Vision); CSI Dry Eye Software; Dompé Pharmaceuticals; Eyederm; Eyenovia; Harrow, Inc; Lumenis; Myze; Nordic Pharma; Norwood Device & Diagnostics; NuLids; Ocubio; PRN Vision Group; Rinsada; SCOPE Health Inc; Sight Sciences; Tarsus Pharmaceuticals, Inc; TearRestore Inc; Viatris Inc (Oyster Point Pharma); Vital Tears LLC; Investment: Barti, Myze, NuLids; Ownership Stake: Eyederm; Executive Team Member: Myze; Medical Director: Norwood Device & Diagnostics


    Faculty, Staff, and Planners’ Disclosures

    In accordance with ACCME Guidelines, PER® has identified and resolved all conflicts of interest for faculty, staff, and planners prior to the start of this activity by using a multistep process.

    The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.

    This podcast, including the narration, was developed by PER® editorial staff based on an online activity developed with these faculty. The narration was voiced by a PER staff member or by an AI tool.

    To learn more about this topic, including further data on neuromodulating dry eye therapies, go to https://www.gotoper.com/boston25optometry-ded-activity 

    Release Date

    January 30, 2026

    Expiration Date

    January 30, 2027

    Off-Label Disclosure and Disclaimer

    This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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