Jesus is said to be indignant on two occasions in the Gospels: when the disciples stopped children approaching Him (Mark 10:14), and here when the man with leprosy approached Him. His indignation (could be translated anger) can be read in a few ways: that the leper wasn’t sure He would be willing to heal him, or that He was angry at how sin had messed this man’s life up, or maybe that He knew the man would ignore His later request to keep quiet.