02.24.2014 - By Billy Lin, MD and Tina Lien, BSc Pharm
Tina discusses the following rhythm control medications for atrial fibrillation:
Class 3 antiarrhythmics: blocks potassium channels and prolongs action potential duration
Amiodarone
Dronedarone
Sotalol
Class 1 antiarrhythmics: blocks sodium channels, which results in a slowed atrial conduction, lengthens atrial refractoriness, and suppresses automaticity
propafenone
flecainide
Indiana University's P450 Drug Interaction Table: http://medicine.iupui.edu/clinpharm/ddis/clinical-table/
References:
CCS Guideline www.onlinecjc.ca/article/S0828-282X(12)00046-3/fulltext
UptoDate uptodate.com
e-CPS www.e-therapeutics.ca/
RXFiles www.rxfiles.ca
Lexicomp www.lexi.com