Join the CADET trial led by Michael Berk: https://impact-trials.deakin.edu.au/trial/cadet-ud-trial/

In this episode, I speaks with Professor Michael Berk, one of the world’s most respected researchers in bipolar science and Director of the IMPACT Institute.

Together, we explore the questions patients and families ask every day but rarely get clear answers to:

• Why do bipolar medications take so long to work?

• Why is bipolar depression often so resistant to treatment?

• What role do genetics, biology, and environment really play?• Could a simple blood pressure medication improve bipolar depression faster?

• How can lifestyle, routines, and social support reduce mood episodes?

• What will it take to finally end the stigma around bipolar disorder?

Professor Berk also explains the promising CADET trial, which studies whether a widely available, low-cost medication could offer a safer and faster option for people with bipolar disorder.

This is a grounded, scientific, and deeply human conversation — offering clarity, hope, and practical insights for anyone touched by bipolar disorder.