In this episode, we are joined by Sarah A. Browne Bradwisch, PhD, RN and Erin Murphy-Smith, MSN, RN to explore the multifaceted implications of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which are widely used for weight management in addition to diabetes treatment. The conversation reviews the pharmacodynamic and physiologic mechanisms of GLP-1 RAs and addresses the clinical, societal, and psychological dimensions of these medications. The speakers emphasize the nurse's role in patient education, the importance of a thorough health history, and the ethical concerns surrounding both the growing trend of online prescriptions without proper health assessments and use of GLP-1 RAs by adolescents. A key takeaway is the need for holistic care—including psychological support—to ensure that weight loss interventions do not lead to unintended harm.

 

Read the related article, "The physiologic and psychologic effects of glucagon-like peptide-1 receptor agonists" in the September issue of Nursing2025.

 

Transcript