Combining disparate datasets and making them accessible to data scientists and researchers is a prevalent challenge for many organizations, not just in healthcare research. American Heart Association (AHA) has built a data science platform using Amazon EMR, Amazon Elasticsearch Service, and other AWS services, that corrals multiple datasets and enables advanced research on phenotype and genotype datasets, aimed at curing heart diseases. In this session, we present how AHA built this platform and the key challenges they addressed with the solution. We also provide a demo of the platform, and leave you with suggestions and next steps so you can build similar solutions for your use cases.