Academic Service Learning is a pedagogical approach to problem-based learning that involves maximizing benefits for both learners and local communities in which educational projects are enacted. This episode describes an ongoing (20-year) project in Ecuador involving faculty from multiple disciplines and multiple universities. Dr. Mario Grijalva, Director of Ohio University’s Infectious and Tropical Disease Institute, and Diana Marvel, Director of Ohio University’s Center for Campus and Community Engagement, describe the service learning project in Ecuador, the philosophy behind service learning, and their approaches to emphasize multidisciplinary work by faculty and student participants. To learn more about this program, visit the ITDI website at: https://www.ohio.edu/medicine/itdi/