Today at ReTuneIn, we welcome Prof. Andrea Kühn and Prof. Jens Volkmann, who share their perspectives on the future of adaptive deep brain stimulation and the evolving landscape of neuromodulation.

Andrea Kühn, Professor of Neurology at Charité Berlin, offers insights into state-dependent stimulation, emerging biomarkers such as gamma activity, and the clinical experience with adaptive DBS in Parkinson’s disease.

Jens Volkmann, Professor of Neurology at the University Hospital Würzburg, reflects on the challenges of translating technological innovation into meaningful patient outcomes, highlighting the role of large-scale data, AI, and personalized stimulation strategies.

Together, they discuss the need to move beyond single-signal approaches, explore dynamic brain states, and rethink how stimulation can better mimic physiological processes—pointing toward the next generation of intelligent, patient-centered neuromodulation therapies.