In this episode of Head and Neck Innovations, Christopher Roxbury, MD, and Rhinology Fellow Chase Kahn, MD, join host Paul Bryson, MD, to discuss advances in endonasal skull base surgery. They explore how the field has evolved, key considerations for patient selection and preoperative planning, and strategies for managing risks such as venous thromboembolism and postoperative bleeding. The conversation also highlights multidisciplinary collaboration and emerging innovations shaping the future of minimally invasive skull base surgery.