Host Dr. Lee Freedman is joined by Francis Marchlinski, MD, Director of Electrophysiology at the University of Pennsylvania Health System; and, the Director of Electrophysiology Laboratory, Hospital of the University of Pennsylvania. In this segment, Dr. Marchlinski discusses premature ventricular contractions (PVCs), when to consider catheter ablation, the use of catheter ablation as primary therapy before medication and epicardial ablation.