There is a bidirectional relationship between cancer and aging. The risk of developing cancer increases as we age, and research shows that cancer and some cancer treatments can accelerate aging. However, earlier detection and targeted therapies are making a difference. Paige Green, chief of the Basic Biobehavioral and Psychological Science Branch, explains that other factors such as psychosocial wellbeing also play a role in the aging process. Green and her colleagues at the National Cancer Institute (NCI) are taking a holistic approach to studying cancer and aging to help survivors lead longer, healthier lives.