What if your AI agent could out-trade institutional desks — from your laptop? In Episode 5 of Dose of Alpha, Bryan Colligan sits down with Taariq Lewis, founder of Seren DB and a crypto OG since 2013, to break down the "Open Claw" world: a future where locally-running AI agents autonomously research, execute, and report on trades — no middlemen, no managed accounts, no waiting on a fund. They cover the rise of autonomous trading agents, why LLMs are powerful but untrustworthy ("they lie"), how AI is the key that finally gets grandma on-chain, and what happens to knowledge workers when agents don't need sleep. 🔑 Topics covered: 0:00 Intro to Taariq Lewis & Seren DB 1:18 From early crypto to AI Agents 3:19 The Open Claw World explained 6:05 Bypassing UI — bringing non-crypto users onchain 8:30 Skills: AI prompts as functional programs 1 4:10 Security risks, scams & LLMs lies 18:17 Human displacement by agents 22:31 Agent-to-agent economies & synthetic currencies 26:00 PolyMarket bots & alpha strategies 27:30 Compute-backed currencies 31:30 Smart Beta: shorting SaaS & infrastructure 38:07 Tokenizing skills for non-crypto users 40:44 How to get started with Seren 🌐 Learn more: serendb.com | 🔗 AlphaGrowth: alphagrowth.io 📲 Follow Bryan: @bryancolligan | @alphagrowth1 More alpha drops soon. #DoseOfAlpha