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Today’s subject: AIDS, and how heat might hold the key to curing it.

AIDS is caused by the HIV virus—a sensitive virus. But here’s the thing about fevers: when you get one, say around 104°F, you’re walking a fine line. That temperature is close to the danger zone where brain damage begins. But not all of your body hits that temperature. The core may spike, but your extremities—fingertips, ears, nose, skin—remain cooler.

And in those cooler areas, the virus survives. It hides. So when your fever breaks, HIV is still there—ready to resume its silent war on your immune system.

Now let’s go back in time—to the 1980s.

A doctor in Italy experimented with five HIV-positive patients. He placed them in sauna baths and elevated their core body temperature to 104°F. He gave them a specific drug that temporarily disabled their heat regulation system, essentially inducing a controlled heat stroke. For six hours, they remained in this hyperthermal state—carefully monitored to avoid crossing into brain damage territory. Afterward, their body temperatures were gradually lowered.

Weeks later, the results were astonishing: three out of the five patients tested negative for HIV. The remaining two tested positive—but both had returned to high-risk behavior and were likely reinfected.

Let that sink in.

A controlled, high-temperature treatment may have wiped out HIV in three patients. But there was no profit in it. No patent. No pharmaceutical company saw dollar signs. So the method was ignored, filed away, and forgotten by mainstream medicine.

Now, there is another method—more drastic.

A bone marrow transplant.

About 2% of people of Northern European descent are naturally immune to HIV. Why? Because their immune cells lack the specific protein HIV needs to latch onto. No protein, no entry. The virus can’t infect them.

Scientists took this knowledge and performed bone marrow transplants on HIV-positive patients—replacing their immune systems with donor marrow from immune individuals. It worked. HIV was eradicated from their bodies.

But this method is risky. Bone marrow transplants are invasive, dangerous, and usually reserved for life-threatening cancers. It’s not something you undergo lightly.

So what’s the takeaway?

There may be multiple paths to an AIDS cure.
One—heat, controlled and sustained.
Two—bone marrow, complex and high-risk.
Three—modern antivirals, effective at extending life, but not a cure.

I’m not a medical doctor. But as the Mad Scientist Supreme, I believe in chasing down cures where others see inconvenience. I believe in simple solutions that can be shared—not patented. And I believe that sometimes, the cure is already known. It’s just been buried.

Cures are the Mad Scientist's domain. Treatments are for those who gave up on a cure.

Live fully. Think freely. Fight the impossible.

This has been the Mad Scientist Supreme, signing off.


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