If you have been a clinician for a number of years, at some point you may well be confronted with a patient who claims to have been "abducted by aliens". Sometimes there is a clear clinical diagnosis; and sometimes something else is going on and you need to be a bit of a detective to figure it out. These cases very often will fall into one of 4 (or perhaps 5) categories - and each category will require a different approach. Let’s take a look at this fascinating subject!