Episode 4 of Brain Explained explores a new theory for understanding pain. Pain, its something we feel often and that many people chronically suffer from with an estimated 40% of people suffering from chronic pain and understanding pain would allow us to help them. That is where Dr Franziska Denk’s Research comes into play. For she is describing a new theory showing that a type of cell called a fibroblasts may be the key player in chronic pain. Listen to the episode to find out how.

Link to Franziska Denk’s lab website

Link to Twitter page for lab

Link to LinkedIn

Links to papers:

Fibroblasts– the neglected cell type in peripheral sensitization and chronic pain? - A systematic view on the current state of the literature.

A transcriptional toolbox for exploring peripheral neuro-immune interactions

Sensitization of Knee-Innervating Sensory Neurons by Tumour Necrosis Factor-α Activated Fibroblast-Like Synoviocytes: An in Vitro, Co-Culture Model of Inflammatory Pain.

Resources:

https://www.coursera.org/learn/statistical-inferences

https://www.franziskadenk.com/resources

https://rna-seq-browser.herokuapp.com/

https://rna-seq-browser.herokuapp.com/

http://mousebrain.org/genesearch.html

https://panglaodb.se/