Super-resolution optical microscopy has become a powerful tool to study the nanoscale spatial distribution of molecules of interest in biological cells, tissues and other structures over the last years. Imaging these distributions in the context of other molecules or the general structural context is, however, still challenging. Jörg Bewersdorf presents recent developments of his lab focusing on instrumentation, fluorescent probes and sample preparation techniques which tackle this challenge. | Jörg Bewersdorf ist Professor für Zellbiologie, Biomedizintechnik und Physik an der Yale University.