Host Ezra Wade explores how chronic loneliness triggers measurable biological damage—spiking cortisol, suppressing immunity, and increasing mortality risk as much as smoking 15 cigarettes daily. Drawing on research from Cacioppo and Holt-Lunstad, the episode reveals why your nervous system can't distinguish social rejection from physical threat, and what small interventions actually help.

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This content was created in partnership and with the help of Artificial Intelligence AI

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