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Alport syndrome occurs due to mutations in COL4A3,4 and 5 genes that encode for collagen type IV alpha subunits 3, 4 and 5 causing kidney issues like hematuria, glomerulonephritis, inner ear problems like sensorineural hearing loss and eye problems like anterior lenticonus.
By nucleotides_bioscienceAlport syndrome occurs due to mutations in COL4A3,4 and 5 genes that encode for collagen type IV alpha subunits 3, 4 and 5 causing kidney issues like hematuria, glomerulonephritis, inner ear problems like sensorineural hearing loss and eye problems like anterior lenticonus.