What is it?

With nutrition we typically think of weight loss, what about brain loss?

Dementia from brain degeneration

Physiology

Slow onset

Prevention and a healthy lifestyle is key

Amyloid plaques/tau proteins

Clumped protein, sticky, kills nerve cell and neuronal connections

Nerves don't innervate other neurons, they become unhealthy-progression of dz

Causes many “mini strokes”.

Berry aneurysms when bad- acute dementia

Causes?

Genetic- nope

Parents have it- its shared lifestyle- we get from parents/family

African American's in Nigeria- 5x less likely then Indianapolis, Indiana- nurture not nature

TBI Head Trauma-

Neuro-inflammation

Post concussion syndrome- symptoms yrs later

Major contributor for many neurological disorders

Vascular- the big one

Cranial atherosclerosis appears #1 cause of alzheimers/dementia

Less blood flow, no O2, neurons die

1quart blood in brain a min

15-20% less by 65yrs

Silent “mini strokes” brain atrophies and plaques

Berry aneurysms- acute dementia

Risk factors- high BP/cholesterol, DM

Nutrition

High sugar/cholesterol

Pro inflam/atherosclerosis

Heavy metals- copper- multi vits unless tested to need it

DM type 2/ “Type 3”

15-20x more likely for alzheimers

Insulin resistance increases amyloid plaque

Oxidized cholesterol

Beta oxidation of fats

Have your veggies/antioxidants

sugar/trans/sat fats except sterate and laureate (lowers LDL)

Chronic Poor Sleep- Glyphatic system

Damaged tau proteins get cleaned in deep sleep

Turn to plaque, cell death

“Graveyard shift”

Higher rate for heart dz, stroke, DM, dementia, CA

Circadian rhythm needs regulation and ran by light

Eating late- dietary circadian rhythm, not as much as tv/cell light

Prevention/symptom assistance

Low Carb/Swank diet/keto

Made for neuro- myelin sheath/ketones

Mediterranean lowest alzheimers rate

olives/fish/veggies

Fasting

Brain Derived Neurotropic Factor learning/memory, makes hippocampus cells

Neurons more resistant to stressors/oxidation

Autophagy of plauqes/dead cells

Lowers insulin resistance/sugar levels

Turmeric/saffron

Slows inflammation, slows amyloid production

 

www.functionised.com

as effective as medications Donepezil (Aricept) and Memantine (Namenda without SIDE EFFECTS in mild/mod/severe Alzhimers

L Citroline- NOS

Increases blood flow to brain-O2, slows plaquing

Inversion therapy, reading, regular exercise,

Healthy lifestyle

 

Functionised Podcast Show Notes