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Ampicillin
Trade NamePrincipen
IndicationSkin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia
ActionBactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death
Therapeutic ClassAnti-infective
Pharmacologic ClassAminopenicillin
Nursing Considerations• Contraindicated in penicillin allergy, use caution in renal insufficiency • May lead to seizures, diarrhea, anaphylaxis, superinfection • Assess for infection • Monitor liver function tests • Instruct patient on signs of superinfection: furry overgrowth on tongue, vaginal itching, loose and foul smelling stool • Pt should not use with oral contraceptive use.
By Jon Haws, RN CCRN Alumnus4.4
157157 ratings
Ampicillin
Trade NamePrincipen
IndicationSkin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia
ActionBactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death
Therapeutic ClassAnti-infective
Pharmacologic ClassAminopenicillin
Nursing Considerations• Contraindicated in penicillin allergy, use caution in renal insufficiency • May lead to seizures, diarrhea, anaphylaxis, superinfection • Assess for infection • Monitor liver function tests • Instruct patient on signs of superinfection: furry overgrowth on tongue, vaginal itching, loose and foul smelling stool • Pt should not use with oral contraceptive use.

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