Animal testing, also known as vivisection, normally elicits strong responses from people, both for and against the procedures. The role of animal experimentation in medical research is controversial, but the British Medical Association is adamant that animal experimentation is necessary to develop a better understanding of diseases and how to treat them. In this podcast, I will explore the reasons why animals are used (in comparison with 'in vitro' studies and computer modelling), how Home Office regulations prevent the abuse of animals, and will describe some of the medical advances made using animal research. (With thanks to our sponsor 'Curriculum Press' for providing content for this podcast)